Clinical Operations

PRA’s Clinical Operations group provides clients with highly-trained, locally-based study teams. Our local project teams develop a strong relationship with each study site, ensuring consummate quality and on-time receipt of all clinical deliverables. PRA's experienced clinical research teams lead the study to ensure a successful site start-up, maintenance and close-out for each trial. Key competencies include: 

  • Knowledge of local regulations and country-specific expertise 
  • Knowledge of medical practices 
  • Safety
  • Therapeutic-specific knowledge

PRA's project start-up services include: 

  • Recruiting investigational sites 
  • Supporting PRA Regulatory Affairs with regulatory authority submissions 
  • Coordinating ethics committee approvals 
  • Collecting and reviewing initial essential documents 
  • Closing investigator contracts (clinical trial agreements) 

PRA clients benefit from a strong support structure for clinical teams. Our in-house clinical research associates (IHCRAs) take responsibility for site management activities and logistics, allowing field CRAs to focus on the most critical aspects of their monitoring visit. 

In-house site management includes: 

  • Reviewing and processing site documents in eTMF (electronic Trial Master File) 
  • Assisting with site queries 
  • Tracking clinical activity status in the PRA Clinical Trial Management System
  • Tracking and assisting with data queries
  • Providing support to CRAs and lead CRAs